Finding the nearest range neighbor in RangedSummarizedExperiment objects

Description

This man page documents the nearest methods and family (i.e. precede, follow, distance, and distanceToNearest methods) for RangedSummarizedExperiment objects.

Usage

## S4 method for signature 'RangedSummarizedExperiment,ANY'
precede(x, subject, select=c("arbitrary", "all"),
        ignore.strand=FALSE)
## S4 method for signature 'ANY,RangedSummarizedExperiment'
precede(x, subject, select=c("arbitrary", "all"),
        ignore.strand=FALSE)

## S4 method for signature 'RangedSummarizedExperiment,ANY'
follow(x, subject, select=c("arbitrary", "all"),
        ignore.strand=FALSE)
## S4 method for signature 'ANY,RangedSummarizedExperiment'
follow(x, subject, select=c("arbitrary", "all"),
        ignore.strand=FALSE)

## S4 method for signature 'RangedSummarizedExperiment,ANY'
nearest(x, subject, select=c("arbitrary", "all"), ignore.strand=FALSE)
## S4 method for signature 'ANY,RangedSummarizedExperiment'
nearest(x, subject, select=c("arbitrary", "all"), ignore.strand=FALSE)

## S4 method for signature 'RangedSummarizedExperiment,ANY'
distance(x, y, ignore.strand=FALSE, ...)
## S4 method for signature 'ANY,RangedSummarizedExperiment'
distance(x, y, ignore.strand=FALSE, ...)

## S4 method for signature 'RangedSummarizedExperiment,ANY'
distanceToNearest(x, subject, ignore.strand=FALSE, ...)
## S4 method for signature 'ANY,RangedSummarizedExperiment'
distanceToNearest(x, subject, ignore.strand=FALSE, ...)

Arguments

Details

These methods operate on the rowRanges component of the RangedSummarizedExperiment object, which can be a GenomicRanges or GRangesList object.

More precisely, if any of the above functions is passed a RangedSummarizedExperiment object thru the x, subject, and/or y argument, then it behaves as if rowRanges(x), rowRanges(subject), and/or rowRanges(y) had been passed instead.

See ?nearest in the GenomicRanges package for the details of how nearest and family operate on GenomicRanges and GRangesList objects.

Value

See ?nearest in the GenomicRanges package.

See Also

• RangedSummarizedExperiment objects.

• The nearest man page in the GenomicRanges package where the nearest family of methods for GenomicRanges and GRangesList objects is documented.

Examples

nrows <- 20; ncols <- 6
counts <- matrix(runif(nrows * ncols, 1, 1e4), nrows)
rowRanges <- GRanges(rep(c("chr1", "chr2"), c(5, 15)),
                     IRanges(sample(1000L, 20), width=100),
                     strand=Rle(c("+", "-"), c(12, 8)))
colData <- DataFrame(Treatment=rep(c("ChIP", "Input"), 3),
                     row.names=LETTERS[1:6])
rse0 <- SummarizedExperiment(assays=SimpleList(counts=counts),
                             rowRanges=rowRanges, colData=colData)
rse1 <- shift(rse0, 100)

res <- nearest(rse0, rse1)
res
stopifnot(identical(res, nearest(rowRanges(rse0), rowRanges(rse1))))
stopifnot(identical(res, nearest(rse0, rowRanges(rse1))))
stopifnot(identical(res, nearest(rowRanges(rse0), rse1)))

res <- nearest(rse0)  # missing subject
res
stopifnot(identical(res, nearest(rowRanges(rse0))))

hits <- nearest(rse0, rse1, select="all")
hits
stopifnot(identical(
  hits,
  nearest(rowRanges(rse0), rowRanges(rse1), select="all")
))
stopifnot(identical(
  hits,
  nearest(rse0, rowRanges(rse1), select="all")
))
stopifnot(identical(
  hits,
  nearest(rowRanges(rse0), rse1, select="all")
))